Discover IXINITY for the treatment of hemophilia B.

IXINITY allows you to define your IXperience.

No longer are people with hemophilia B (also known as Christmas disease) defined by their condition—they're defined by their abilities and their passions.

IXINITY is a blood-clotting medicine for hemophilia B. IXINITY has an average incremental recovery of 98%.1 Higher recovery may allow lower doses. IXINITY also has a terminal half-life of 24 hours,1 which allows for peak factor levels when you need them.

A different IXperience for people with hemophilia B.

John Taylor's Hemophilia B Journey

The founder of the Coalition for Hemophilia B and the father of a son with hemophilia B shares his inspiring story of hope.

Women and girls can—and do—have hemophilia B.

Aptevo Therapeutics worked with women who have hemophilia B to create a quick guide that focuses on how this condition affects women, girls, and their families.

With help from this guide, you can feel confident talking about your symptoms with your doctor or nurse.

IXINITY is now brought to you by Aptevo Therapeutics — a company that's anything but ordinary

Aptevo Therapeutics is a new biotech company focused on novel treatments for people with bleeding disorders and cancer. The scientists at Aptevo discover new ways of meaningfully improving lives by mixing their vast experience with a personal drive to push forward the science of what’s next.

When it comes to the hemophilia B community, the same people from Emergent who pride themselves on working for a different kind of company are now part of Aptevo. So while you may see a new business card, IXINITY [coagulation factor IX (recombinant)] is still the same, and you’ll still connect with the same Product Specialist and the rest of the people you’ve come to trust.

Learn more about Aptevo Therapeutics.

Reference: 1. IXINITY [coagulation factor IX (recombinant)] prescribing information. Berwyn, PA: Aptevo BioTherapeutics LLC; August 2016.



What is IXINITY®?

IXINITY [coagulation factor IX (recombinant)] is a medicine used to replace clotting factor (factor IX) that is missing in adults and children at least 12 years of age with hemophilia B. Hemophilia B is also called congenital factor IX deficiency or Christmas disease. Hemophilia B is an inherited bleeding disorder that prevents clotting. Your healthcare provider may give you IXINITY to control and prevent bleeding episodes or when you have surgery.

IXINITY is not indicated for induction of immune tolerance in patients with hemophilia B.


  • You should not use IXINITY if you are allergic to hamsters or any ingredients in IXINITY.
  • You should tell your healthcare provider if you have or have had medical problems, take any medicines, including prescription and non-prescription medicines, such as over-the-counter medicines, supplements, or herbal remedies, have any allergies, including allergies to hamsters, are nursing, are pregnant or planning to become pregnant, or have been told that you have inhibitors to factor IX.
  • You can experience an allergic reaction to IXINITY. Contact your healthcare provider or get emergency treatment right away if you develop a rash or hives, itching, tightness of the throat, chest pain, or tightness, difficulty breathing, lightheadedness, dizziness, nausea, or fainting.
  • Your body may form inhibitors to IXINITY. An inhibitor is part of the body's defense system. If you develop inhibitors, it may prevent IXINITY from working properly. Consult with your healthcare provider to make sure you are carefully monitored with blood tests for development of inhibitors to IXINITY.
  • If you have risk factors for developing blood clots, the use of IXINITY may increase the risk of abnormal blood clots.
  • Call your healthcare provider right away about any side effects that bother you or do not go away, or if your bleeding does not stop after taking IXINITY.
  • The most common side effect that was reported with IXINITY during clinical trials was headache.
  • These are not all the side effects possible with IXINITY. You can ask your healthcare provider for information that is written for healthcare professionals.

For more information about IXINITY, please see full Prescribing Information, including Important Patient Information.

You are encouraged to report side effects of prescription drugs to the Food and Drug Administration. Visit, or call 1-800-FDA-1088.